| Title | Weekend | Total | Analysis |
| Transformers: Dark of the Moon | $47M | $261M | After just two weeks, this robot sequel is the top-grossing movie for 2011 |
| Horrible Bosses | $28.1M | $28.1M | Upset win over Zookeeper yet no match for Transformers 3 |
| Zookeeper | $21M | $21M | Modest opening for poorly reviewed zoo-themed take on Mall Cop |
| Cars 2 | $15.2M | $148.8M | Fading quickly from scene well before reaching $200M budget mark |
| Bad Teacher | $9M | $78.8M | Not a Bridesmaids smash, but certainly one of 2011's surprise hits |