Rebooting novelist James Patterson's famous Alex Cross character for the big screen, Tyler Perry aims at new cinematic territory and scores a bullseye as the Detroit detective embroiled in a hunt for a mega-evil killer that turns personal.
—Peter Hammond Box Office Magazine
A disjointed thriller with two many characters rattling around.
—Roger Ebert Chicago Sun Times
Miscast and underwritten, Alex Cross does not reinvent Tyler Perry, or James Patterson's character, or anything, really. The only appeal here is the sick kick of watching a franchise blow itself to bloody stumps.
—Ken McIntyre Total Film
In the face of such junk, the idea that Fox would proudly put himself on a punishing regime of severe diet and exercise to get prisoner-skinny-yet-crazy-muscled for the job of make-believe is vanity at best, obscenity at worst.
—Lisa Schwarzbaum Entertainment Weekly
The cross-dressing "Madea" star seems out of his depth playing the hard-boiled detective made famous by Morgan Freeman in "Along Came a Spider" and "Kiss the Girls." Even action helmer Rob Cohen ("The Fast and the Furious," "XXX") seems to be off his game here.
—Peter Debruge Variety